Project 1

Chen W, Giger ML, Bick U.  A fuzzy c-means (FCM) based approach for computerized segmentation of breast lesions in dynamic contrast-enhanced MR images.  Academic Radiology 2006 Jan;13:63-72

Chen W, Giger ML, Bick U, Newstead G. Automatic identification and classification of characteristic kinetic curves of breast lesions on DCE-MRI. Medical Physics, 2006 Aug; 33:2878-2887

Chen W, Giger ML, Li H, Bick U, Newstead. Volumetric texture analysis of breast    lesions on contrast-enhanced magnetic resonance images. Magnetic Resonance in Medicine, 2007 Sept; 58:562-571

Li H, Giger ML, Olopade OI, Lan L. Fractal Analysis of Mammographic Parenchymal Patterns in Breast Cancer Risk Assessment. Academic Radiology 2007 May; 14:513-521

Yuan Y, Giger ML, Li H, Suzuki K, Sennett C.  A dual-stage method for lesion segmentation on digital mammograms, Medical Physics 2007 Nov; 34:4180-4193

Li H, Giger ML, Olopade OI, Chinander MR. Power Spectral Analysis of Mammographic Parenchymal Patterns of Digitized Mammograms. J Digital Imaging 2008 Jun; 21(2):145-52

Drukker K, Gruszauskas N, Sennett CA, Giger ML. Breast Ultrasound Computer-Aided Diagnosis: Performance on a Large Clinical Diagnostic Population. Radiology 2008 Aug; 248(2):392-7

Horsch K, Giger ML, Metz CE. Prevalence Scaling: Applications to an Intelligent Workstation for the Diagnosis of Breast Cancer Academic Radiology. Academic Radiology 2008 Nov; 15(11):1446-57

Gruszauskas N, Drukker K, Giger ML, Sennett CA, Pesce LL. Performance of breast ultrasound computer aided diagnosis: Dependence on image selection. Academic Radiology 2008 Oct; 15(10):1234-45

Project 2

Medved M, Newstead GM, Abe H, Zamora MA, Olopade OI, Karczmar GS. High spectral and spatial resolution MRI of breast lesions: preliminary clinical experience. Am J Roentgenol 186:30-37, 2006.

Fan X, Medved M, Karczmar GS, Yang C, Foxley S, Arkani S, Recant W, Zamora MA, Abe H, Newstead GM. Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI. Magn Reson Med 25:593-603, 2007.

Jansen SA, Newstead GM, Abe H, Shimauchi A, Schmidt RA, Karczmar GS. Pure ductal carcinoma in situ: kinetic and morphologic MR characteristics compared with mammographic appearance and nuclear grade. Radiology 245:684-691, 2007.

Puri N, Khramtsov A, Ahmed S, Nallasura V, Hetzel JT, Jagadeeswaran R, Karczmar G, Salgia R. A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts. Cancer Research 67:3529-3534, 2007.

Yang C, Karczmar GS, Medved M, Stadler WM. Multiple reference tissue method for contrast agent arterial input function estimation. Magn Reson Med 58:1266-1275, 2007.

Jansen SA, Fan X, Karczmar GS, Abe H, Schmidt RA, Newstead GM. Differentiation between benign and malignant breast lesions detected by bilateral dynamic contrast-enhanced MRI: A sensitivity and specificity study. Magn Reson Med 59:747-754, 2008.

Jansen SA, Conzen SD, Fan X, Krausz T, Zamora M, Foxley S, Newstead GM, Karczmar GS. Detection of in situ mammary cancer in a transgenic mouse model: in vitro and in vivo MRI studies demonstrate histopathologic correlation. Physics in Medicine and Biology, 2008 Oct 7; 53(19) 5481-93.

Jansen SA, Fan X, Karczmar GS, Abe H, Schmidt RA, Giger ML, Newstead GM. DCEMRI of Breast lesions: Is kinetic analysis equally effective for both mass and non-mass-like enhancement? Medical Physics 2008 Jul; 35(7): 3102-9.

Project 3

Huo D, Kim HJ, Adebamowo CA, Ogundiran TO, Akang EE, Campbell O, Adenipekun A, Niu Q, Sveen L, Fackenthal JD, Fackenthal DL, Das S, Cox N, Rienzo AD, Olopade OI. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and breast cancer risk in Africans. Breast Cancer Res Treat. 2008 Jul;110(2):367-76

Project 4

Huang RS, Duan S, Kistner EO, Hartford CM, Dolan ME. Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans. Molecular Cancer Therapy 2008 Sep;7(9):3038-46.